(±)-2′-Phenylcyclohexanespiro-4′-(azepano[1,2-b]isoxazolidine)
نویسندگان
چکیده
In the crystal structure of the racemic title isoxazolidine, C(19)H(27)NO, the relative stereochemistry between the phenyl group and the bridgehead H atom is shown to be syn. There are two mol-ecules in the asymmetric unit, one of which is the 7R*,13R* enanti-omer, and one of which is the 7S*,13S* enanti-omer. These enanti-omers adopt different orientations of the phenyl ring with respect to the isoxazolidine ring, with C-C-C-C torsion angles of 63.6 (4) and 86.8 (4)°, respectively. In both enanti-omers, the six-membered ring adopts a chair conformation, while the seven-membered ring adopts a twist-chair conformation.
منابع مشابه
Methyl 5-hydroxy-3-phenyl-1,2-oxazolidine-5-carboxylate
In the title compound, C(11)H(13)NO(4), the isoxazolidine ring has an envelope conformation with the O atom as the flap. In the crystal, mol-ecules are liked via N-H⋯O and bifurcated O-H⋯(O,N) hydrogen bonds forming chains propagating along [010]. There are also C-H⋯O inter-actions present.
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